A potent new synthetic opioid has been linked with a death in Australia.

Health officials from various Australian states have reported cases of protonitazene use and its association with an Adelaide man's tragic death, as well as multiple overdoses. 

The drug has been detected in Victoria, Queensland, and most recently, South Australia.

Protonitazene, a synthetic opioid, poses a severe threat even in minute quantities. 

According to South Australia's acting chief public health officer, Chris Lease, it can lead to "lethal" toxic effects at very low doses. 

The drug is three times stronger than fentanyl and 130 times more potent than morphine, according to Drug and Alcohol Services South Australia's acting state director, Victoria Cock.

What makes this drug even more perilous is that it is frequently found mixed with other substances, including methamphetamine, GHB, and ketamine. 

Dr Cock warns that all recreational drug users are at risk, not just those who use opioids. 

Taking even the slightest overdose can have disastrous consequences, causing respiratory failure.

The symptoms of an overdose include small pupils, shallow breathing, drowsiness, and a sudden deterioration of one's condition. Experts say those around the affected individuals are more likely to notice the signs, and it is crucial for them to immediately seek medical help.

In terms of harm reduction measures, it can be important to use drugs in a group or public space to ensure timely access to medical assistance if needed. Additionally, users should only consume very tiny amounts of protonitazene. 

Furthermore, recreational drug users can access naloxone, a vital antidote for protonitazene, available at pharmacies and in the form of a take-home spray or preloaded injectable syringe.

As the origins of the drug remain uncertain, authorities have identified its presence not only in Australia but also in the US, Canada, and other states and territories. 

The drug has appeared in various forms, including disguised as genuine medications, making it difficult to trace and prevent its circulation.